Accutane (isotretinoin) is an efficient retinoid used for the treatment of severe acne in patients that did not benefit from using other drugs. In fact, you will need to present proof you tried other ways of treating your acne. Your acne may get worse at first, but this is a normal skin reaction, and it means Accutane is actually working right for you. Make sure you take it regularly until you notice an improvement. It may take you several weeks to see the first results of the treatment. Side effects of Accutane are not too serious and include the following symptoms: sore lips, flushing, nosebleeds, cold symptoms, dry mouth, tiredness, voice changes, hair loss, sweating, dry skin, slowed healing of cuts, changes in the nails, and changes in skin color. If you have taken too much of Accutane and get any of the following overdose symptoms - seek emergency medical help: vomiting, swelling of the lips, dizziness, tingling under the skin, stomach pain, loss of balance, or headache. Taking a double dose or just using more of Accutane than necessary is not going to make the treatment more effective. Make sure you always follow the directions provided.